Joseph Sinacori, PA-C, MBA is the co-founder and Chief Operating Officer of Bespoke Aesthetics — bringing a rare combination of clinical expertise, healthcare leadership, and genuine passion for helping people live longer, healthier, and more vibrant lives.
Joseph’s medical career spans Internal Medicine and Cardiology, where he built a reputation for precision, leadership, and a deep commitment to patient outcomes. During his time at NYU Winthrop Hospital in Mineola, NY, he led a hospital-wide quality initiative that earned him a distinction no other Physician Assistant had achieved — his project was one of only four selected to be showcased at the graduation ceremony, where he was the sole PA in the room.
That same drive for excellence followed him into the world of longevity and wellness medicine. Joseph holds a certification from SSRP — Seeds Scientific Research & Performance — and now sees patients at Bespoke for hormone therapy, peptide therapy, medical weight loss, and comprehensive health and wellness optimization. His approach is rooted in the science of optimization — helping patients build a foundation of health that supports how they look, how they feel, and how they age.
As COO, Joseph leads the operational and strategic vision of Bespoke, ensuring that every patient experience reflects the boutique, personalized standard that the practice was built on.
Outside of the office, Joseph is a creature of habit in the best way — spending his weekends on the golf course and returning year after year to Montalcino, Italy, where he has developed a deep love for collecting Brunello di Montalcino wine. He is a devoted husband and father, and he brings that same sense of care and intention to every patient he sees.
